Aromatase inhibitor — Aromatase inhibitors (AI) are a class of drugs used in the treatment of breast cancer and ovarian cancer in postmenopausal women that block the aromatase enzyme.Type I and IIAIs are categorized into two types: [cite journal |author=Mokbel K… … Wikipedia
Aromatase inhibitor — A drug that inhibits the enzyme aromatase and thus lowers the level of the estrogen, estradiol. Aromatase inhibitors are a class of antiestrogens. Aromatase catalyzes the conversion of testosterone (an androgen) to estradiol (an estrogen) in… … Medical dictionary
aromatase inhibitor — A drug that prevents the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy for postmenopausal women who have hormone dependent breast cancer … English dictionary of cancer terms
Aromatase — Bändermodell nach PDB … Deutsch Wikipedia
Aromatase — Cytochrome P450, family 19, subfamily A, polypeptide 1 Crystallographic structure of the human aromatase cytochrome P450 (rainbow colored cartoon, N terminus = blue, C terminus = red) in complex with the cofactor protoporphyrin IX (top) and the… … Wikipedia
nonsteroidal aromatase inhibitor — A drug that decreases the production of sex hormones (estrogen or testosterone) and slows the growth of tumors that need sex hormones to grow … English dictionary of cancer terms
inhibitor — 1. An agent that restrains or retards physiologic, chemical, or enzymatic action. 2. A nerve, stimulation of which represses activity. SEE ALSO: inhibition. α glucosidase i. an oral agent that aids in th … Medical dictionary
Monoamine oxidase inhibitor — MAOI redirects here. For the Easter Island statues, see Moai. Monoamine oxidase Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. They are particularly effective in treating… … Wikipedia
Phosphodiesterase inhibitor — A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and… … Wikipedia
Dihydrofolate reductase inhibitor — A dihydrofolate reductase inhibitor is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate. Since folate is needed by rapidly dividing cells to make thymine, this effect may be used to therapeutic… … Wikipedia